Isotopically Labeled Compounds
Cambridge Isotope Laboratories Toluene-d8 (d, 99.5%), 2037-26-5, MFCD00044638, 10 g
Chemical Formula: C6D5CD3, MW: 100.19, 99.5%.
Medchemexpress LLC Sinapyl alcohol-d3 5mg
Sinapyl alcohol-d3 is the deuterated labeled Sinapyl alcohol (HY-W109812) Sinapyl alcohol is an orally active anti-inflammatory and antinociceptive agent Sinapyl alcohol reduces the expression level of inducible NO synthase and COX-2[1]
Medchemexpress LLC Pirfenidone-d5 | 1020719-62-3 | MFCD07369537 | 98.9% | 190.25 g/mol | C12H6D5NO | 10 MG
Pirfenidone-d5 is the deuterium-labeled isotopologue of pirfenidone used as an analytical reference and internal standard in quantitative mass spectrometry and pharmacokinetic studies. It provides a chemically similar labeled compound for accurate quantitation of pirfenidone in biological and biochemical assays.
- Deuterium-labeled internal standard for LC-MS/MS assays
- High purity (~98.9%) suitable for analytical use
- Molecular weight 190.25 g/mol; formula C12H6D5NO
- Available as a 10 mg vial for laboratory use
- Suitable for pharmacokinetic and metabolic studies
Cambridge Isotope Laboratories SPIRULINA WHOLE CELLS (LYOPHILIZED POWDER) (U-13C, 97%+), 1 G
SPIRULINA WHOLE CELLS (LYOPHILIZED POWDER) (U-13C, 97%+), 1 G
Medchemexpress LLC DL-Xylose | 25990-60-7 | MFCD00198055 | 98.0% | 1 ML
DL-Xylose is an organic synthesis intermediate, appearing as a white to off-white solid. This compound is intended for research applications only.
- Organic synthesis intermediate
- For research use only
- Soluble in water and PBS
Medchemexpress LLC Entacapone-d10 | 1185241-19-3 | 98.6% | C14H5D10N3O5 | 500 UG
Entacapone-d10 is a deuterium-labeled Entacapone. Entacapone is a potent, reversible, peripherally acting, and orally active catechol-O-methyltransferase (COMT) inhibitor. It inhibits COMT from rat brain, erythrocytes, and liver with IC50 values of 10 nM, 20 nM, and 160 nM, respectively. It is selective for COMT over other catecholamine metabolizing enzymes like MAO-A, MAO-B, phenolsulphotransferase M (PST-M), and PST-P (IC50s>50 μM). Entacapone also inhibits FTO demethylation with an IC50 of 3.5 μM.
- Can be used as a tracer.
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium-labeled compound for drug development quantitation.
- Potentially affects pharmacokinetic and metabolic profiles of drugs.
- Useful for Parkinson's disease research.
- Applicable for metabolic disorder research.
Cambridge Isotope Laboratories ETHANOL (2-13C, 99%) (, 1 G, 14770-41-3
ETHANOL (2-13C, 99%) (, 1 G, 14770-41-3
Cambridge Isotope Laboratories LAURIC ACID (1-13C, 99%), 5 G, 93639-08-8
LAURIC ACID (1-13C, 99%), 5 G, 93639-08-8
Cambridge Isotope Laboratories SODIUM BUTYRATE (1-13C, 99%), 5 G, 62601-04-1
SODIUM BUTYRATE (1-13C, 99%), 5 G, 62601-04-1
Cambridge Isotope Laboratories L-LEUCINE-N-T-BOC:H2O (2-13C, 99%), 0.25 G
L-LEUCINE-N-T-BOC:H2O (2-13C, 99%), 0.25 G
Medchemexpress LLC Cetrimonium-d9 bromide | 95217-14-4 | 50 MG
Cetrimonium-d9 (bromide) is the deuterium-labeled Cetrimonium bromide. Cetrimonium bromide (CTAB) is an amine-based cationic quaternary surfactant, and a component of the topical antiseptic Cetrimide. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Isoxsuprine-d6 (hydrochloride) | 2706004-35-3 | 99.9% | 500 UG
Isoxsuprine-d6 (hydrochloride) is the deuterium-labeled Isoxsuprine hydrochloride. Isoxsuprine hydrochloride is a beta-adrenergic receptor agonist with Kis of 13.65 μΜ and 3.48 μΜ for myometrial and placental beta-adrenergic receptors, respectively. It is also an NMDA receptor antagonist.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Nicosulfuron-d6 | 1189419-41-7 | 98.4% | 1 MG
Nicosulfuron-d6 is a deuterium-labeled version of Nicosulfuron, a selective herbicide from the sulfonylurea family. It is commonly applied as a post-emergence herbicide to safeguard maize crops from weeds by inhibiting the activity of the acetolactate synthase (ALS) enzyme.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium substitution can impact the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Taurocholic acid-d4 | 252030-90-3 | 99.5% | 100 UG
Taurocholic acid-d4 is deuterium labeled Taurocholic acid, a bile acid involved in the emulsification of fats. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled for use as a tracer
- Involved in fat emulsification
- Suitable for quantitative analysis
- Potential to affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Prucalopride-13C,d3 | 2140306-00-7 | 99.0% | C1713CH23D3CIN3O3 | 1 MG
Prucalopride-13C,d3 is the 13C- and deuterium labeled Prucalopride, used largely as a tracer for quantitation during drug development. Deuteration has potential to affect the pharmacokinetic and metabolic profiles of drugs. This product has not been fully validated for medical applications and is for research use only.
- Stable heavy isotopes incorporated into drug molecules
- Potential to affect pharmacokinetic and metabolic profiles of drugs
- Target: 5-HT receptor
- Pathway: GPCR/G protein; neuronal signaling